Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Lactate Dehydrogenase Isoenzyme V Rabbit mAb [64G82]
抗Lactate Dehydrogenase Isoenzyme V兔单克隆抗体 [64G82]
Cat. No.
A52206
Clone No. 64G82
SynonymsLactate Dehydrogenase Isoenzyme V, LDH-V, LDH-A, Lactate dehydrogenase M chain
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
36 kDa
Observed MW
36 kDa
Clonality
Monoclonal
Clone No.
64G82
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
LDHA
Protein Name
Lactate dehydrogenase A (LDHA)
Background
Lactate Dehydrogenase Isoenzyme V (LDH5) is a tetrameric L-lactate dehydrogenase isozyme composed of four LDHA subunits, localized in cytoplasm. It catalyzes terminal glycolytic reaction: reduction of pyruvate to lactate, regenerating NAD+ to sustain glycolysis especially under hypoxia. LDH5 is a central effector of Warburg effect. It is frequently over-expressed in tumors, driving lactate production and remodeling tumor microenvironment.
Localization
Cytoplasm
Research Area
代谢
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:500-1:2000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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