Anti-LRP1 Rabbit mAb [52D71]

抗LRP1兔单克隆抗体 [52D71]

Cat. No. A52208 Clone No. 52D71

SynonymsLRP1, LRP, LDL receptor-related protein 1, APOE receptor

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
85 kDa
Observed MW
85 kDa
Clonality
Monoclonal
Clone No.
52D71
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
LRP1
Protein Name
Low-density-lipoprotein receptor-related protein-1
Background
LRP1 (Low-density lipoprotein receptor-related protein 1) is a transmembrane receptor of LDL-receptor superfamily, broadly expressed across cell types. It mediates endocytic clearance of diverse ligands including lipoproteins, protease-inhibitor complexes and growth factors, and also participates in signal transduction. LRP1 contributes to lipid homeostasis, protein turnover and vascular biology. It exerts context-dependent pro- or anti-tumor effects by modulating proliferation and migration.
Localization
Cell membrane
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 4035 Q07954
Mouse 16971 Q91ZX7

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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