Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-KDM1A Rabbit mAb [73G33]
抗KDM1A兔单克隆抗体 [73G33]
Cat. No.
A52209
Clone No. 73G33
SynonymsKDM1A, LSD1, BHC110, KDM1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
93 kDa
Observed MW
110 kDa
Clonality
Monoclonal
Clone No.
73G33
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
KDM1A
Protein Name
Lysine-specific histone demethylase-1A
Background
KDM1A (Lysine-specific demethylase 1A, LSD1) is a nuclear epigenetic enzyme belonging to histone lysine demethylase family. It catalyzes demethylation of histone H3K4me1/me2 and H3K9me1/me2 to remodel chromatin status and fine-tune gene transcription. KDM1A maintains stem-cell pluripotency and orchestrates cell differentiation. Its aberrant over-expression promotes oncogenesis, rendering KDM1A an attractive target for epigenetic anti-cancer drug development.
Localization
Nucleus
Research Area
表观遗传学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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