Anti-N6-methyladenosine (m6A) Rabbit mAb [44B57]

抗N6-methyladenosine (m6A)兔单克隆抗体 [44B57]

Cat. No. A52212 Clone No. 44B57

SynonymsN6-methyladenosine (m6A), m⁶A

Host species Rabbit
Reactivity Species independent
Applications Dot blot

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Modification
Methyl
Clonality
Monoclonal
Clone No.
44B57
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Protein Name
N6-methyladenosine (m6A)
Background
m6A (N6-methyladenosine) is the most abundant epitranscriptomic modification on mRNA, representing a nucleoside chemical mark rather than a protein family. It shapes RNA fate by regulating splicing, nuclear export, translational output and RNA stability or decay. m6A marks are deposited by writer complexes, erased by demethylases and decoded by reader proteins. m6A participates in stem-cell differentiation, stress responses and oncogenesis; global m6A profiles are perturbed in many cancers.
Localization
Nucleus
Research Area
表观遗传学

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

Dot blot
1:500-1:2000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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