Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-METTL3 Rabbit mAb [08B58]
抗METTL3兔单克隆抗体 [08B58]
Cat. No.
A52215
Clone No. 08B58
SynonymsMETTL3, Methyltransferase-like 3, KAT22
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
64 kDa
Observed MW
70 kDa
Clonality
Monoclonal
Clone No.
08B58
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
METTL3
Protein Name
Methyltransferase-like-3
Background
METTL3 (Methyltransferase-like 3) is the core catalytic subunit of nuclear m6A methyltransferase writer complex. It heterodimerizes with METTL14 and catalyzes N6-methyladenosine (m6A) deposition onto mRNA and other RNA species. METTL3 controls RNA processing and metabolism, and is essential for embryogenesis and stem-cell differentiation. Dysregulated METTL3 promotes tumor proliferation and metastasis. METTL3 is a central epitranscriptomic target.
Localization
Nucleus
Research Area
表观遗传学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:400
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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