Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-MiTF Rabbit mAb [24G60]
抗MiTF兔单克隆抗体 [24G60]
Cat. No.
A52216
Clone No. 24G60
SynonymsMiTF, MITF, Microphthalmia transcription factor, MiF
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
58 kDa
Observed MW
58 kDa
Clonality
Monoclonal
Clone No.
24G60
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MITF
Protein Name
Microphthalmia-associated transcription factor
Background
MiTF (Microphthalmia-associated transcription factor) is a nuclear bHLH-LZ (basic-helix-loop-helix-leucine-zipper) transcription factor. It governs transcriptional programs of melanocyte lineage, controlling melanocyte differentiation, melanin biosynthesis and cell survival. Loss-of-function MiTF leads to microphthalmia and pigmentary disorders. Amplification or over-expression of MiTF drives malignant phenotypes in melanoma. MiTF serves as a key biomarker for melanocytes and melanoma.
Localization
Nucleus
Research Area
癌症
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:500
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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