Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-MMP13 Rabbit mAb [62G36]
抗MMP13兔单克隆抗体 [62G36]
Cat. No.
A52217
Clone No. 62G36
SynonymsMMP13, MMP-13, Collagenase-3
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
60 kDa
Observed MW
60 kDa
Clonality
Monoclonal
Clone No.
62G36
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MMP13
Protein Name
Matrix metallopeptidase-13
Background
MMP13 (Matrix metalloproteinase-13) is a zinc-dependent secreted protease of MMP family, synthesized as pro-enzyme and activated to degrade extracellular-matrix components. It exhibits preferential catalytic activity toward type-II collagen and participates in bone remodeling, cartilage turnover and tissue repair. Pathological MMP13 up-regulation drives cartilage destruction in osteoarthritis and facilitates tumor invasion-metastasis; its expression is strongly induced by inflammatory cytokines.
Localization
Secreted
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:500-1:2000
IHC
1:100-1:500
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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