50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
74 kDa
Observed MW
64 kDa
Clonality
Monoclonal
Clone No.
40B79
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
MMP2
Protein Name
Matrix metallopeptidase-2
Background
MMP2 (Matrix metalloproteinase-2) is a secreted zinc-dependent gelatin-subfamily matrix metalloproteinase. It degrades gelatin and type-IV collagen to dismantle basement-membrane barriers and mediates tissue remodeling and angiogenesis. MMP2 is secreted as inactive pro-MMP2 and gets activated via extracellular proteolytic cleavage. Elevated MMP2 accelerates tumor invasion and metastasis.