Anti-MMP2 Rabbit mAb [40B79]

抗MMP2兔单克隆抗体 [40B79]

Cat. No. A52218 Clone No. 40B79

SynonymsMMP2, MMP-2, Gelatinase A, MMP-2,72kDa gelatinase

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
74 kDa
Observed MW
64 kDa
Clonality
Monoclonal
Clone No.
40B79
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
MMP2
Protein Name
Matrix metallopeptidase-2
Background
MMP2 (Matrix metalloproteinase-2) is a secreted zinc-dependent gelatin-subfamily matrix metalloproteinase. It degrades gelatin and type-IV collagen to dismantle basement-membrane barriers and mediates tissue remodeling and angiogenesis. MMP2 is secreted as inactive pro-MMP2 and gets activated via extracellular proteolytic cleavage. Elevated MMP2 accelerates tumor invasion and metastasis.
Localization
Secreted
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 4313 P08253
Mouse 17390 P33434

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:2000-1:10000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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