Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Mucin 5AC Rabbit mAb [93B45]
抗Mucin 5AC兔单克隆抗体 [93B45]
Cat. No.
A52227
Clone No. 93B45
SynonymsMucin 5AC, MUC5AC, Gastric mucin, MUC5AC
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
586 kDa
Observed MW
586 kDa
Clonality
Monoclonal
Clone No.
93B45
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MUC5AC
Protein Name
Mucin-5AC
Background
MUC5AC (Mucin-5AC, mucin 5AC, oligomeric mucus/gel-forming) belongs to gel-forming secreted mucin family and mediates gel-mucus biosynthesis and epithelial protection in respiratory and gastric tissues. Produced by airway goblet cells and gastric surface epithelial cells, heavily O-glycosylated MUC5AC forms hydrated gel to trap pathogens and particles, mitigating chemical and mechanical epithelial damage. MUC5AC is abundant in normal gastric mucosa. Elevated MUC5AC represents hallmark mucus hypersecretion in asthma, chronic bronchitis and COPD. Aberrant MUC5AC expression occurs in gastric and biliary carcinoma and serves as pathological biomarker.
Localization
Secreted
Research Area
细胞生物学
数据库链接
| 物种 Organism | 基因 ID | SwissProt |
|---|---|---|
| Human | P98088 |
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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