Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Sodium Potassium ATPase Rabbit mAb [63B76]
抗Sodium Potassium ATPase兔单克隆抗体 [63B76]
Cat. No.
A52228
Clone No. 63B76
SynonymsSodium Potassium ATPase, Na⁺/K⁺-ATPase, Na+/K+ ATPase alpha-1, ATPase Na+/K+ transporting subunit alpha-1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
113 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
63B76
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
ATP1A1
Protein Name
Sodium-potassium transporting ATPase
Background
Na+/K+-ATPase (Sodium-potassium adenosine triphosphatase) is a P-type ATPase transporter family protein that catalyzes transmembrane Na+/K+ exchange to sustain plasma membrane electrochemical gradient. Hydrolyzing one ATP molecule, it extrudes three Na+ out and imports two K+ into cytoplasm, maintaining resting potential, osmotic balance and nutrient co-transport. Ubiquitously present on plasma membrane, it is highly enriched in epithelium, neuron and cardiomyocyte. It supports nerve impulse propagation, cardiac contraction and renal tubular reabsorption. Its inhibition disturbs ionic homeostasis and induces apoptosis. Subunit remodeling of Na+/K+-ATPase occurs in human tumors and correlates with proliferation and migration.
Localization
Cell membrane
Research Area
代谢
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:20000-1:50000
IHC
1:2000-1:10000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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