Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Nanog Rabbit mAb [05F76]
抗Nanog兔单克隆抗体 [05F76]
Cat. No.
A52229
Clone No. 05F76
SynonymsNanog, NANOG homeobox, PGC-4
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
42 kDa
Observed MW
42 kDa
Clonality
Monoclonal
Clone No.
05F76
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
NANOG
Protein Name
Homeobox protein NANOG
Background
Nanog (Homeobox transcription factor Nanog) is a homeobox transcription-factor family protein maintaining pluripotency and repressing differentiation in stem cells. Predominantly expressed in embryonic stem cells and iPSCs, Nanog cooperates with Oct4 and Sox2 to form core pluripotency circuitry. It binds target promoters to activate stemness genes and silence differentiation programs. Its expression level dictates pluripotent status: high Nanog preserves undifferentiated state, while its down-regulation triggers germ-layer differentiation. It is barely detectable in most adult tissues but re-activated in cancer stem cells to drive self-renewal, invasion and metastasis.
Localization
Nucleus
Research Area
干细胞
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。