Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-p38 Rabbit mAb [06F52]
抗p38兔单克隆抗体 [06F52]
Cat. No.
A52256
Clone No. 06F52
Synonymsp38, p38 MAPK, p38α MAPK, p38-alpha MAPK, PRKM14
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
41 kDa
Observed MW
41 kDa
Clonality
Monoclonal
Clone No.
06F52
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
MAPK14
Protein Name
Mitogen-activated protein kinase-14 (p38-α)
Background
p38 MAPK (Mitogen-activated protein kinase 14) belongs to MAP kinase family and transduces cellular stress, inflammatory, apoptotic and differentiation signals. p38 is a serine-threonine kinase activated via upstream MAP2K-mediated dual phosphorylation upon pro-inflammatory cytokines, oxidative stress, UV irradiation and osmotic challenge. Activated p38 translocates into nucleus and phosphorylates transcription factors to modulate transcription of pro-inflammatory, apoptotic and cell-cycle target genes. It mediates innate immunity and cytokine production, as well as cell differentiation and senescence. Sustained p38 signaling contributes to autoimmunity, inflammatory disorders and tumor progression.
Localization
Cytoplasm
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:50-1:300
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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