Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Rad51 Rabbit mAb [69H64]
抗Rad51兔单克隆抗体 [69H64]
Cat. No.
A52289
Clone No. 69H64
SynonymsRad51, RAD51 recombinase, D5S214, DSS1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
37 kDa
Observed MW
37 kDa
Clonality
Monoclonal
Clone No.
69H64
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
RAD51
Protein Name
RAD51 recombinase
Background
RAD51 (RAD51 recombinase) belongs to recombinase family and executes homologous-recombination repair of DNA double-strand breaks to safeguard genome stability. Upon double-strand break formation, RAD51 is recruited to lesion sites, displaces RPA on single-stranded DNA and assembles nucleoprotein filaments that drive homologous strand-exchange for HR-mediated repair. RAD51 serves as central HR effector and contributes to DNA-damage response and meiotic recombination. BRCA1-BRCA2 facilitates RAD51 loading; BRCA-deficient tumors exhibit impaired RAD51 foci formation.
Localization
Nucleus
Research Area
癌症
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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