Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-RhoA Rabbit mAb [14E24]
抗RhoA兔单克隆抗体 [14E24]
Cat. No.
A52292
Clone No. 14E24
SynonymsRhoA, RhoA GTPase, RAS-related C3 botulinum toxin substrate
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
21 kDa
Observed MW
21 kDa
Clonality
Monoclonal
Clone No.
14E24
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
RHOA
Protein Name
RhoA GTPase
Background
RHOA (RhoA, Ras-homolog family member A) belongs to Rho small-GTPase family acting as molecular switch for actin cytoskeleton remodeling, stress-fiber and focal-adhesion assembly, controlling cellular contraction, migration and invasion. GTP-bound active RhoA localizes at inner plasma membrane and activates downstream effectors such as ROCK, promoting myosin phosphorylation, stress-fiber formation and cell contractility. GDP-loaded RhoA resides in cytosol in inactive state. Its cycling is tightly controlled by GEF, GAP and GDI proteins; GPCR and extracellular-matrix cues trigger RhoA activation. Hyper-activated RhoA fuels tumor migration and invasion.
Localization
Cytoplasm
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。