Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-SOD2 Rabbit mAb [13B91]
抗SOD2兔单克隆抗体 [13B91]
Cat. No.
A52313
Clone No. 13B91
SynonymsSOD2, Manganese superoxide dismutase, MnSOD, SODM, ALS8
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
25 kDa
Observed MW
22 kDa
Clonality
Monoclonal
Clone No.
13B91
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
SOD2
Protein Name
Superoxide dismutase-2, mitochondrial
Background
SOD2 (Superoxide dismutase 2, Mn-SOD) is manganese-dependent mitochondrial superoxide dismutase localized in mitochondrial matrix, responsible for scavenging respiratory-chain-derived superoxide radicals and preserving mitochondrial redox homeostasis. Using manganese co-factor, SOD2 detoxifies matrix superoxide and shields mitochondrial DNA and respiratory complexes from oxidative damage as key mitochondrial antioxidant enzyme. SOD2 down-regulation amplifies oxidative stress and contributes to ageing, inflammation and cardiovascular disorders. SOD2 exerts dual roles in malignancies: insufficient SOD2 aggravates oxidative damage while moderate up-regulation confers tumour-cell resistance against ROS stress.
Localization
Mitochondrion
Research Area
代谢
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。