Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-SP1 Rabbit mAb [96A09]
抗SP1兔单克隆抗体 [96A09]
Cat. No.
A52315
Clone No. 96A09
SynonymsSP1, SP-1, E4F, GC box binding factor
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
100 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
96A09
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
SP1
Protein Name
Sp1 transcription factor
Background
SP1 (Sp1 transcription factor) belongs to Sp/KLF zinc-finger transcription-factor family that recognizes GC-box cis-elements and governs transcription of numerous house-keeping and proliferation-associated genes. Predominantly nuclear-localized, SP1 binds GC-rich promoter sequences and modulates genes involved in cell-cycle progression, apoptosis, metabolism and angiogenesis, participating in cell-growth control and stress responses. SP1 function is fine-tuned by post-translational modifications and protein abundance. SP1 is frequently overexpressed in tumours, driving oncogenic-gene transcription and correlating with poor clinical prognosis.
Localization
Nucleus
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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