Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-STAT3 (phospho Ser727) Rabbit mAb [10H81]
抗STAT3 (phospho Ser727)兔单克隆抗体 [10H81]
Cat. No.
A52321
Clone No. 10H81
SynonymsSTAT3 (phospho Ser727), p-STAT3(Ser727), STAT3, APRF, Signal transducer and activator of transcription 3, Acute-phase response factor
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
88 kDa
Observed MW
88 kDa
Modification
Phospho
Clonality
Monoclonal
Clone No.
10H81
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
STAT3
Protein Name
STAT3 (phospho Ser727)
Background
STAT3 Ser727 is serine-phosphorylation site targeted by kinases including MAPK and PKC, functionally distinct from JAK-dependent Tyr705 activating motif. Ser727 phosphorylation modulates STAT3 transcriptional potency and protein stability, and also promotes STAT3 mitochondrial translocation to regulate mitochondrial respiration and ROS production. Biological outcomes of Ser727 modification are context-dependent, either potentiating or restraining STAT3-dependent transcription and mediating pathway crosstalk.
Localization
Nucleus
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:400-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。