Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-STAT5A Rabbit mAb [47D84]
抗STAT5A兔单克隆抗体 [47D84]
Cat. No.
A52322
Clone No. 47D84
SynonymsSTAT5A, STAT5, Signal transducer and activator of transcription 5A
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
91 kDa
Observed MW
91 kDa
Clonality
Monoclonal
Clone No.
47D84
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
STAT5A
Protein Name
Signal transducer and activator of transcription-5A
Background
STAT5A (Signal transducer and activator of transcription 5A) belongs to JAK-STAT-family and transduces signals downstream of growth hormone, prolactin and multiple interleukins, governing proliferation, differentiation, mammary-gland lactogenesis and haematopoiesis. Upon cytokine stimulation, JAK-mediated phosphorylation at conserved tyrosine residue drives STAT5A homo- or heterodimerization and nuclear translocation for target-gene transcription. STAT5A shares high sequence homology with STAT5B yet executes partially-distinct tissue-specific functions; STAT5A is critical for mammary-gland development and lactation. Constitutive STAT5A activation contributes to haematological malignancies.
Localization
Cytoplasm, Nucleus
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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