Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-STAT5 (phospho Tyr694) Rabbit mAb [54G18]
抗STAT5 (phospho Tyr694)兔单克隆抗体 [54G18]
Cat. No.
A52323
Clone No. 54G18
SynonymsSTAT5 (phospho Tyr694), p-STAT5(Tyr694), STAT5A, STAT5, Signal transducer and activator of transcription 5A, STAT5B, Signal transducer and activator of transcription 5B
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
91 kDa
Observed MW
105 kDa
Modification
Phospho
Clonality
Monoclonal
Clone No.
54G18
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
STAT5A, STAT5B
Protein Name
STAT5 (phospho Tyr694)
Background
STAT5 Tyr694 represents conserved JAK-phosphorylation site on STAT5A/STAT5B and serves as STAT5-pathway activation marker. Stimulated by cytokines, growth hormone or prolactin, JAK kinases catalyse tyrosine-phosphorylation at STAT5A-Tyr694 and orthologous STAT5B-Tyr699, triggering STAT5 dimerization, nuclear translocation and downstream-gene transcription to regulate haematopoiesis, immunity and mammary-cell proliferation-differentiation.
Localization
Cytoplasm, Nucleus
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IHC
1:100-1:500
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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