50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
91 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
14E04
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
STAT5A, STAT5B
Protein Name
STAT-5A and STAT-5B
Background
STAT5A/B denotes two highly-homologous JAK-STAT-family paralogs. This pan-STAT5 antibody detects total protein of both STAT5A and STAT5B isoforms. STAT5A/B transduce cytokine, growth-hormone and prolactin signals, participating in haematopoietic-cell differentiation, immune responses and mammary-gland development. They exhibit substantial functional redundancy alongside isoform-specific physiological roles. Constitutive STAT5 activation drives leukaemia, lymphoma and other haematological neoplasms.