Anti-STAT5A/B Rabbit mAb [14E04]

抗STAT5A/B兔单克隆抗体 [14E04]

Cat. No. A52324 Clone No. 14E04

SynonymsSTAT5A/B, STAT5A, STAT5, Signal transducer and activator of transcription 5A, STAT5B, Signal transducer and activator of transcription 5B

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
91 kDa
Observed MW
100 kDa
Clonality
Monoclonal
Clone No.
14E04
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
STAT5A, STAT5B
Protein Name
STAT-5A and STAT-5B
Background
STAT5A/B denotes two highly-homologous JAK-STAT-family paralogs. This pan-STAT5 antibody detects total protein of both STAT5A and STAT5B isoforms. STAT5A/B transduce cytokine, growth-hormone and prolactin signals, participating in haematopoietic-cell differentiation, immune responses and mammary-gland development. They exhibit substantial functional redundancy alongside isoform-specific physiological roles. Constitutive STAT5 activation drives leukaemia, lymphoma and other haematological neoplasms.
Localization
Cytoplasm, Nucleus
Research Area
免疫和传染性疾病
数据库链接
物种 Organism基因 IDSwissProt
Human 6776; 6777 P42229; P51692
Mouse 20850; 20851

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:2000-1:10000
IHC
1:2000-1:8000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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