Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
抗Polycomb Protein SUZ12兔单克隆抗体 [36G88]
Cat. No.
A52332
Clone No. 36G88
SynonymsPolycomb Protein SUZ12, SUZ12, EEDC2, polycomb protein Suz12, EZH2 interacting protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
83 kDa
Observed MW
83 kDa
Clonality
Monoclonal
Clone No.
36G88
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
SUZ12
Protein Name
SUZ12 polycomb repressive complex-2 subunit
Background
SUZ12 (SUZ12 polycomb repressive complex 2 subunit) is core structural subunit of PRC2 (Polycomb-Repressive Complex 2), mediating epigenetic silencing via histone H3K27 methylation of developmental target genes. SUZ12 acts as scaffold maintaining PRC2 complex integrity for EZH2 and EED. PRC2 catalyzes H3K27me2/me3 marks to condense chromatin and repress differentiation-associated genes, sustaining stem-cell pluripotency. SUZ12 ablation disrupts PRC2 function; aberrant SUZ12 expression contributes to oncogenesis.
Localization
Nucleus
Research Area
表观遗传学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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