Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-TDP43 Rabbit mAb [02A16]
抗TDP43兔单克隆抗体 [02A16]
Cat. No.
A52339
Clone No. 02A16
SynonymsTDP43, TDP-43, TDP-43, ALS4, TAR DNA binding protein
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
45 kDa
Observed MW
45 kDa
Clonality
Monoclonal
Clone No.
02A16
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
TARDBP
Protein Name
TAR DNA-binding protein-43
Background
TARDBP (TDP-43) is RNA-binding protein regulating RNA splicing, trafficking and transcript stability, predominantly localized in nucleus. Physiologically TDP-43 executes post-transcriptional mRNA control. In ALS and frontotemporal dementia (FTD), TDP-43 mis-localizes to cytoplasm, undergoes hyper-phosphorylation, ubiquitination and forms cytoplasmic inclusions, constituting hallmark lesions of TDP-43 proteinopathies.
Localization
Nucleus
Research Area
神经科学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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