Anti-TSG101 Rabbit mAb [32E51]

抗TSG101兔单克隆抗体 [32E51]

Cat. No. A52351 Clone No. 32E51

SynonymsTSG101, HIV-TAR RNA-binding protein, p95, TSG101

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IP, IF, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
44 kDa
Observed MW
44 kDa
Clonality
Monoclonal
Clone No.
32E51
Isotype
IgG, Kappa

抗原与靶点信息 Antigen & Target Information

Gene Name
TSG101
Protein Name
Tumor susceptibility gene-101
Background
TSG101 (Tumor susceptibility gene 101) is core subunit of ESCRT-I complex, mediating multivesicular-body (MVB) biogenesis, endosomal cargo sorting, vesicle budding and exosome biogenesis. As part of ESCRT-I machinery, TSG101 sorts ubiquitinated membrane cargoes into MVBs for lysosomal degradation; it also supports viral budding and cytokinetic abscission. TSG101 perturbation disturbs membrane-protein homeostasis and contributes to oncogenesis.
Localization
Cytoplasm
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 7251 Q99816
Mouse 22088 Q61187

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:5000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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