Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-TWIST1 Rabbit mAb [03E77]
抗TWIST1兔单克隆抗体 [03E77]
Cat. No.
A52355
Clone No. 03E77
SynonymsTWIST1, Twist-related transcription factor 1, TWIST1, Twist-1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
21 kDa
Observed MW
26 kDa
Clonality
Monoclonal
Clone No.
03E77
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
TWIST1
Protein Name
Twist-related protein-1
Background
TWIST1 is bHLH-family transcription factor and master transcriptional driver of epithelial-mesenchymal transition (EMT). Nuclear TWIST1 represses epithelial genes such as E-cadherin and up-regulates mesenchymal transcripts to confer migratory-invasive properties. It participates in embryogenesis and wound repair. Aberrant TWIST1 activation in tumours promotes invasion-metastasis, stem-cell-like traits and chemoresistance.
Localization
Nucleus
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:2000-1:10000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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