Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-Ubiquitin Lys48 Rabbit mAb [14A03]
抗Ubiquitin Lys48兔单克隆抗体 [14A03]
Cat. No.
A52356
Clone No. 14A03
SynonymsUbiquitin Lys48, Ubiquitin(K48-linkage), Ubiquitin K48-linked polyubiquitin chain, Ubiquitin-42Y
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
26 kDa
Observed MW
13-250 kDa
Clonality
Monoclonal
Clone No.
14A03
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
UBC
Protein Name
Ubiquitin(K48-linkage)
Background
K48-linked polyubiquitin chains are assembled via lysine-48 of ubiquitin moieties and constitute canonical targeting signal for proteasomal degradation. Substrates decorated with K48 polyubiquitin are recognized by 26S proteasome for ubiquitin-proteasome-system-dependent turnover, governing cell-cycle progression, DNA-damage response, apoptosis and general protein homeostasis.
Localization
Cytoplasm
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:500-1:2000
IHC
1:200-1:1000
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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