Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-UCP1 Rabbit mAb [65F39]
抗UCP1兔单克隆抗体 [65F39]
Cat. No.
A52357
Clone No. 65F39
SynonymsUCP1, Uncoupling protein 1, UCP1, UCP, thermogenin
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
33 kDa
Observed MW
33 kDa
Clonality
Monoclonal
Clone No.
65F39
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
UCP1
Protein Name
Uncoupling protein-1
Background
UCP1 (Uncoupling protein 1) resides in inner mitochondrial membrane of brown adipocytes. It mediates proton leak, uncouples oxidative-phosphorylation ATP-production from respiratory-chain electron flow and dissipates energy as heat to accomplish non-shivering thermogenesis. UCP1 serves as specific biomarker for brown adipocytes. Cold exposure and β-adrenergic signalling up-regulate UCP1 to trigger thermogenesis.
Localization
Mitochondrion
Research Area
代谢
数据库链接
| 物种 Organism | 基因 ID | SwissProt |
|---|---|---|
| Mouse | P12242 |
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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