Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-XBP1 Rabbit mAb [95B03]
抗XBP1兔单克隆抗体 [95B03]
Cat. No.
A52365
Clone No. 95B03
SynonymsXBP1, X-box binding protein 1, XBP1, XBP-1
详细信息 Product Information
Buffer
50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
29 kDa
Observed MW
35 kDa, 60 kDa
Clonality
Monoclonal
Clone No.
95B03
Isotype
IgG, Kappa
抗原与靶点信息 Antigen & Target Information
Gene Name
XBP1
Protein Name
X-box-binding protein-1
Background
XBP1 (X-box-binding protein 1) is master transcription factor of endoplasmic-reticulum-stress UPR (unfolded-protein-response) pathway. Accumulation of misfolded proteins activates IRE1, which mediates XBP1-mRNA splicing to generate potent active spliced isoform XBP1-s. Nuclear XBP1-s up-regulates ER-folding and ER-associated-degradation transcripts to resolve ER stress. Unspliced XBP1-u exhibits minimal transcriptional activity.
Localization
Nucleus
Research Area
细胞生物学
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:1000-1:5000
IHC
1:200-1:1000
IP
1:50-1:200
IF
1:200-1:1000
ELISA
1:5000-1:20000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
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