50% Glycerol, 0.05% BSA and 0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
0.2 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
61 kDa
Observed MW
70 kDa
Clonality
Monoclonal
Clone No.
84C59
Isotype
IgG, Kappa
抗原与靶点信息
Antigen & Target Information
Gene Name
YTHDF1
Protein Name
YTH domain-containing family-1
Background
YTHDF1 is m6A RNA-methylation reader protein. It recognizes N6-methyladenosine modification on mRNA, binds target transcripts and boosts translation efficiency of m6A-marked mRNAs to remodel protein output. It participates in cell proliferation, differentiation and oncogenesis and serves as key effector within m6A epitranscriptomic circuitry.