Anti-Caspase-9 Mouse mAb [96E74]
WBIHCIPIF
Anti-IRF-3 Rabbit pAb (A72132)
抗IRF-3兔多克隆抗体
Cat. No.
A72132
SynonymsIRF-3, ISGF3 gamma, NF-IL6
详细信息 Product Information
Buffer
50% Glycerol, 0.5% BSA and 0.02% preservative in PBS (pH 7.2-7.4)
Purification
Antigen-affinity-purified
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
47 kDa
Observed MW
48-55 kDa
Clonality
Polyclonal
Isotype
IgG
抗原与靶点信息 Antigen & Target Information
Gene Name
IRF3
Protein Name
Interferon regulatory factor-3
Domain
human IRF3, aa 362-411
Background
IRF3 (Interferon regulatory factor 3) belongs to IRF transcription-factor family and resides in cytoplasm under resting conditions. It governs innate immune transcriptional programs: upon activation of cytosolic pattern-recognition receptors, IRF3 undergoes phosphorylation and dimerization, translocates into nucleus and triggers transcription of type-I interferons and antiviral genes. IRF3 is central for antiviral innate immunity; its dysfunction impairs host antiviral defense. Aberrant IRF3 activation contributes to inflammatory pathologies.
Localization
Cytoplasm, Nucleus
Research Area
免疫和传染性疾病
实验信息 Product Usage & Documents
推荐稀释比 Recommended Dilution
WB
1:500-1:2000
IHC
1:100-1:300
IF
1:50-1:200
ELISA
1:5000
以上为起始稀释比建议，实际需按样本类型与显色体系优化。
相关产品 Related Products
Anti-IL-1β Rabbit mAb [99F42]
WBIPIFELISA
Anti-Polycomb Protein SUZ12 Rabbit mAb [36G88]
WBIHCIPIFELISA
价格与规格
该产品暂未录入规格价格，请联系我们获取报价与现货情况。