Anti-β-Tubulin (Acetyl Lys379) Rabbit pAb (A72230)

抗β-Tubulin (Acetyl Lys379)兔多克隆抗体

Cat. No. A72230

Synonymsβ-Tubulin (Acetyl Lys379), Ac-β-Tubulin(Lys379), Tubulin beta-2A chain

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, ELISA

详细信息 Product Information

Buffer
50% Glycerol, 0.5% BSA and 0.02% preservative in PBS (pH 7.2-7.4)
Purification
Antigen-affinity-purified
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
50 kDa
Observed MW
50 kDa
Modification
Acetyl
Clonality
Polyclonal
Isotype
IgG

抗原与靶点信息 Antigen & Target Information

Gene Name
TUBB
Protein Name
β-Tubulin (Acetyl Lys379)
Background
β-Tubulin belongs to tubulin family and controls microtubule dynamics, cell division and molecular motor anchoring. β‑Tubulin forms heterodimers with α‑Tubulin and constitutes microtubule plus end, governing dynamic instability for microtubule growth and shrinkage. Multiple tissue-specific β-tubulin isoforms exist, such as neuron-specific βIII-Tubulin (Tuj1) involved in neuronal differentiation. β-Tubulin is stably expressed across most cell types and used as loading control for WB and IF. Isoform switching or mutations may confer resistance to taxane-class microtubule-targeting drugs. It is widely applied in cytoskeleton, mitosis, neuronal differentiation and anti-tumour drug resistance researches.
Localization
Cytoplasm
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 7280 Q13885; Q9BVA1; Q13509; P04350; P68371; P07437; Q9BUF5
Mouse 22151 Q7TMM9

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:2000
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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