Anti-CD68 Rabbit pAb (A73004)

Protein A affinity purification

CD68 molecule

CD68 (Lysosomal-associated membrane glycoprotein CD68) belongs to mucin-like transmembrane glycoprotein family and executes lysosomal-endosomal trafficking and macrophage identification functions. Predominantly localized on lysosomal and endosomal membranes of monocytes and macrophages, small fraction of CD68 is displayed on cell surface. It participates in intracellular lysosomal substance transport and degradation. CD68 is a routine marker for monocyte-macrophage lineage to label tissue-resident macrophages and tumor-associated macrophages. Notably, CD68 cannot distinguish M1/M2 polarization states; low-level expression is also observed on dendritic cells and certain activated myeloid cells.

Lysosome