Anti-Hsp90 Rabbit pAb (A73088)

抗Hsp90兔多克隆抗体

Cat. No. A73088

SynonymsHsp90, HSP90, HSP90 aa1, EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p

Host species Rabbit
Reactivity Human, Mouse, Rat
Applications WB, IHC, ICC/IF, ELISA

详细信息 Product Information

Buffer
0.05% preservative in PBS (pH 7.2-7.4)
Purification
Protein A affinity purification
Concentration
1 mg/ml
Storage
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Calculated MW
85 kDa
Clonality
Polyclonal
Isotype
IgG

抗原与靶点信息 Antigen & Target Information

Gene Name
HSP90AA1
Protein Name
Heat-shock-protein-90-alpha
Background
Hsp90 (Heat shock protein 90) is an Hsp90-family molecular chaperone abundant in cytoplasm, with isoforms present in ER and mitochondria. It orchestrates folding and conformational stabilization of client proteins including kinases and transcription factors to enable their functional maturation. Hsp90 governs signaling cascades controlling cell proliferation, survival and migration. Many oncogenic drivers rely on Hsp90 for stability; Hsp90 up-regulation sustains malignant phenotypes in tumors, making Hsp90 a promising anti-cancer drug target.
Localization
Cytoplasm
Research Area
细胞生物学
数据库链接
物种 Organism基因 IDSwissProt
Human 3326 P08238
Mouse 15516 P11499

实验信息 Product Usage & Documents

推荐稀释比 Recommended Dilution

WB
1:1000-1:2000
IHC
1:200-1:2000
ICC/IF
1:100-1:500
ELISA
1:5000-1:20000
以上为起始稀释比建议,实际需按样本类型与显色体系优化。

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