Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping
Frozen
Form
Liquid
Observed MW
78 kDa
Clonality
Polyclonal
Isotype
IgG
抗原与靶点信息
Antigen & Target Information
Gene Name
MMP9
Protein Name
Matrix metalloproteinase-9
Background
MMP9 (Matrix metalloproteinase-9) is a secreted zinc-dependent gelatin-family matrix metalloproteinase. It degrades gelatin and type-IV collagen to break down basement-membrane barriers, supporting inflammatory-cell infiltration, tissue remodeling and angiogenesis. Secreted as pro-MMP9, it gains activity through extracellular processing and is strongly induced by inflammatory stimuli. Elevated MMP9 promotes tumor invasion-metastasis and contributes to neuroinflammation and cardiovascular disorders.